Neuropeptide S (human) (TFA)
CAS No. ——
Neuropeptide S (human) (TFA) ( —— )
产品货号. M30292 CAS No. ——
Neuropeptide S human (TFA) is a potent endogenous neuropeptide S receptor agonist (EC50=9.4 nM).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
100MG | 获取报价 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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100MG | 获取报价 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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生物学信息
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产品名称Neuropeptide S (human) (TFA)
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Neuropeptide S human (TFA) is a potent endogenous neuropeptide S receptor agonist (EC50=9.4 nM).
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产品描述Neuropeptide S human (TFA) is a potent endogenous neuropeptide S receptor agonist (EC50=9.4 nM). (In Vitro):Neuropeptide S (human)(4 pM to 1.7 nM; 48 hours) retains full agonist activity with an EC50?of 6.7 ± 2.4 nM, the binding of [125I] Y10-hNPS to CHO cells stably expressing hNPSR is saturable with high affinity (Kd?= 0.33 ± 0.12 nM). Neuropeptide S (human)(1 pM-3 μM; 48 hours) are used to compete with 0.15 nM [125II] Y10-NPS, [125II] Y10-NPS is displaceable by increasing concentrations of human NPS (IC50?= 0.42 ± 0.12 nM)?.(In Vivo):Neuropeptide S human (TFA)(intracerebroventricular (i.c.v.) injection; 0.1 nM or 1 nM; 60 mins) causes a significant increase in locomotor activity, the total distance traveled, percentage of time moving, number of rearing events, and center entries are also significantly increased in mice.
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同义词——
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通路Others
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靶点Other Targets
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受体EC50: 9.4 nM (neuropeptide S receptor)
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研究领域——
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适应症——
化学信息
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CAS Number——
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分子量2301.5
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分子式C95H156N31F3O30S
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称Sequence:{Ser}{Phe}{Arg}{Asn}{Gly}{Val}{Gly}{Thr}{Gly}{Met}{Lys}{Lys}{Thr}{Ser}{Phe}{Gln}{Arg}{Ala}{Lys}{Ser}
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
Xu YL, et al. Neuropeptide S: a neuropeptide promoting arousal and anxiolytic-like effects.Neuron. 2004 Aug 19;43(4):487-97.
产品手册
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